abstract：OBJECTIVE:To describe our early experience with robotic-assisted laparoscopy for extraperitoneal para-aortic lymphadenectomy up to the left renal vein, including Da Vinci robot positioning. METHODS:Six patients underwent robotic-assisted laparoscopy using the Da Vinci apparatus. The patients included a man with a pT2 ...

journal_title：Gynecologic oncology

authors： Narducci F,Lambaudie E,Houvenaeghel G,Collinet P,Leblanc E

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:Recent prospective data support the trend towards systematic retroperitoneal lymphadenectomy in patients with high-risk endometrial cancer. Because para-aortic node involvement in the absence of pelvic node involvement is uncommon, a reliable finding of negative pelvic lymph nodes (PLN) at intraoperative froz...

journal_title：Gynecologic oncology

authors： Pristauz G,Bader AA,Regitnig P,Haas J,Winter R,Tamussino K

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:BRCA1 mutation carriers have a high rate of both breast and ovarian cancer. Tamoxifen is a selective estrogen receptor modulator (SERM), which is used for the treatment of primary breast cancer and for the prevention of contralateral breast cancer. Our objective is to assess if tamoxifen treatment is associat...

journal_title：Gynecologic oncology

authors： Vicus D,Rosen B,Lubinski J,Domchek S,Kauff ND,Lynch HT,Isaacs C,Tung N,Sun P,Narod SA,Hereditary Ovarian Cancer Clinical Study Group.

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to determine whether ovarian preservation is feasible in younger endometrial cancer patients. METHODS:Endometrial cancer patients who underwent ovary-saving surgery were recruited from the tumor registries of 14 tertiary hospitals under the influence of the Korean Gynecologic...

journal_title：Gynecologic oncology

authors： Lee TS,Kim JW,Kim TJ,Cho CH,Ryu SY,Ryu HS,Kim BG,Lee KH,Kim YM,Kang SB,Korean Gynecologic Oncology Group.

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:The oncogenic HPV subtypes responsible for gynecologic malignancies have also been implicated in the development of squamous cell cancer of the anus (SCAC). SCAC is more common in women, typically presenting at an older age than gynecologic cancers. The aim of this study was determine whether women diagnosed ...

journal_title：Gynecologic oncology

authors： Jiménez W,Paszat L,Kupets R,Wilton A,Tinmouth J

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVES:Pegylated liposomal doxorubicin is one of the preferred alternatives for ovarian cancer patients with early relapse (<6 months) and taxane/carboplatin for late relapse (>12 months), but the optimal therapy for the partially platinum-sensitive (6-12 months) population has not been defined. This single-arm pha...

journal_title：Gynecologic oncology

authors： Power P,Stuart G,Oza A,Provencher D,Bentley JR,Miller WH Jr,Pouliot JF

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVE:To determine if the timing of normalization of CA-125 levels during primary chemotherapy for epithelial ovarian cancer (EOC) could predict survival. METHODS:Patients who reached a complete clinical response for EOC with primary taxane/platinum-based chemotherapy were eligible. Patient demographics, chemother...

journal_title：Gynecologic oncology

authors： Rocconi RP,Matthews KS,Kemper MK,Hoskins KE,Huh WK,Straughn JM Jr

更新日期：2009-08-01 00:00:00

abstract：:The thoroughness of cytoreductive surgery is the largest contributor to survival for patients with advanced ovarian and primary peritoneal carcinoma. For many years the surgery undertaken by Gynaecologic Oncologists has been tailored to match their surgical training. Future surgical training of Gynaecologic Oncologist...

journal_title：Gynecologic oncology

authors： Crandon AJ,Obermair A

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVE:The aim of this trial was to investigate the efficacy and toxicity of a relative high-dose of topotecan combined with carboplatin in recurrent or persistent epithelial ovarian cancer (EOC). METHODS:Patients participating in this phase II trial received topotecan at a dose of 1.0 mg/m(2)/day intravenously (IV...

journal_title：Gynecologic oncology

authors： Kang H,Kim TJ,Lee YY,Choi CH,Lee JW,Bae DS,Kim BG

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVE:Local cervical factors may determine the outcome of human papillomavirus (HPV) infection. Nitric oxide (NO) may be one such factor, since it is produced by uterine cervical cells and it takes part in both immunological and carcinogenic reactions. We studied the association between the presence of cervical hig...

journal_title：Gynecologic oncology

authors： Rahkola P,Mikkola TS,Ylikorkala O,Vaisanen-Tommiska M

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVE:While primary cisplatin-based intraperitoneal chemotherapy has been shown to favorably impact survival in small-volume residual advanced ovarian cancer, there is a need to develop strategies that improve the effectiveness of this approach. METHODS:A multi-center phase 2 trial was conducted that added intrave...

journal_title：Gynecologic oncology

authors： Smith HO,Moon J,Wilczynski SP,Tiersten AD,Hannigan EV,Robinson WR,Rivkin SE,Anderson GL,Liu PY,Markman M

更新日期：2009-08-01 00:00:00

abstract：INTRODUCTION:The rationale for lymphadenectomy in primary peritoneal cancer (PPC) is unclear. We sought to define the pattern of lymphatic metastasis in PPC and propose evidence-based rationale for lymphadenectomy in relevant cases. METHODS:Patients with PPC undergoing primary surgery at Mayo Clinic were identified. D...

journal_title：Gynecologic oncology

authors： Aletti GD,Powless C,Bakkum-Gamez J,Wilson TO,Podratz KC,Cliby WA

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVES:The goal of this case review was to evaluate the influence of complete surgical versus clinical staging, including the impact of ovarian preservation, on the outcome of young patients with endometrial carcinoma. METHODS:A retrospective chart review was performed on all patients with endometrial cancer diagn...

journal_title：Gynecologic oncology

authors： Richter CE,Qian B,Martel M,Yu H,Azodi M,Rutherford TJ,Schwartz PE

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVES:Although many clinicians practice empiric dose reduction to prevent toxicity, it is unknown whether obese patients given chemotherapy dosed according to actual body weight (ABW) experience excess toxicity. At our institution, cancer patients receive chemotherapy dosed by ABW unless on a protocol capping dose...

journal_title：Gynecologic oncology

authors： Schwartz J,Toste B,Dizon DS

更新日期：2009-07-01 00:00:00

abstract：:Endometrial cancer is the most common gynecologic malignancy in the Western world and is strongly associated with obesity. Despite the fact that most cases are diagnosed in early, more favorable stages, endometrial cancer incidence and mortality rates are on the rise. Morbidly obese women with endometrial cancer are m...

journal_title：Gynecologic oncology

authors： Fader AN,Arriba LN,Frasure HE,von Gruenigen VE

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVES:Endometrioid adenocarcinoma of the endometrium (EEC) is the most common histologic type of endometrial cancer, with stage being the most critical prognostic factor. Cervical involvement (CI), divided into IIA (epithelial involvement) and IIB (stromal invasion), is overall associated with decreased survival (...

journal_title：Gynecologic oncology

authors： Orezzoli JP,Sioletic S,Olawaiye A,Oliva E,del Carmen MG

更新日期：2009-06-01 00:00:00

abstract：:As gynecologic surgeons garnered a better understanding of various clinical-pathological prognostic factors, there evolved a number of modifications in the surgical approach allowing for more individualized therapy with less morbidity, while still retaining the curative potential of the radical vulvectomy operation. T...

journal_title：Gynecologic oncology

authors： Moore DH

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to determine whether thromboembolic events (TE) in cervical cancer patients are associated with survival by comparing the survival of patients with and without thromboembolic events over a seven year period. METHODS:Utilizing a retrospective chart review we identified patients ...

journal_title：Gynecologic oncology

authors： Jacobson G,Lammli J,Zamba G,Hua L,Goodheart MJ

更新日期：2009-05-01 00:00:00

abstract：OBJECTIVES:Determinants of endometrial cancer grade have not been precisely defined, however, cell cycle control is considered to be integrally involved in endometrial cancer development. TP53 and MDM2 are essential components for cell cycle arrest and apoptosis. Polymorphisms in these genes cause TP53 inactivation and...

journal_title：Gynecologic oncology

authors： Ashton KA,Proietto A,Otton G,Symonds I,McEvoy M,Attia J,Gilbert M,Hamann U,Scott RJ

更新日期：2009-04-01 00:00:00

abstract：:Epithelial ovarian cancer (EOC) has a relatively high mortality rate ( approximately 55%). One of the presiding causes is that the current chemotherapeutic regimes are unable to achieve sustained remission, despite frequently producing a positive response at first treatment. One of the reasons that EOC is difficult to...

journal_title：Gynecologic oncology

authors： Shield K,Ackland ML,Ahmed N,Rice GE

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:While ovarian borderline tumors are common, their fallopian tube counterparts are extremely rare. We describe the first case of a serous borderline paratubal tumor with a review of the literature on paratubal and tubal low malignant potential tumors. CASE:A 26 year-old woman presented with acute onset of sh...

journal_title：Gynecologic oncology

authors： Seamon LG,Holt CN,Suarez A,Richardson DL,Carlson MJ,O'Malley DM

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:Given the paucity of data regarding the patterns of metastasis from ovarian sex cord-stromal tumors (SCSTs), we sought to determine the risk of lymph node metastasis in patients with SCSTs. METHODS:A retrospective chart review was performed after clinical and pathology databases were queried for ovarian SCST...

journal_title：Gynecologic oncology

authors： Brown J,Sood AK,Deavers MT,Milojevic L,Gershenson DM

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:The primary objective of the study was to prospectively assess quality of life (QOL) among women at increased risk of ovarian cancer who are undergoing risk-reducing salpingo-oophorectomy (RRSO) or serial screening. METHODS:Women at increased risk of ovarian cancer who were undergoing RRSO were recruited int...

journal_title：Gynecologic oncology

authors： Fang CY,Cherry C,Devarajan K,Li T,Malick J,Daly MB

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVE:Recent scientific advances have lead to the development of a prophylactic, quadrivalent HPV vaccine conferring. We surveyed Latino and non-Latino women directly to examine what motivates them to vaccinate themselves, their daughters, and their sons. METHODS:A written survey was administered to 86 Latinas and...

journal_title：Gynecologic oncology

authors： Watts LA,Joseph N,Wallace M,Rauh-Hain JA,Muzikansky A,Growdon WB,del Carmen MG

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVES:The precise role of gonadotropins in the carcinogenesis of epithelial ovarian cancer remains uncertain. Recently, the haplotype of two single nucleotide polymorphisms, Thr307Ala (rs6165) and Asn680Ser (rs6166), has been described as a risk factor for ovarian cancer in Chinese women. In this study we investig...

journal_title：Gynecologic oncology

authors： Heubner M,Riemann K,Otterbach F,Kimmig R,Kasimir-Bauer S,Siffert W,Wimberger P

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVE:Data has suggested obesity as an independent prognostic factor for lower survival in patients with epithelial ovarian cancer (EOC). We sought to determine if obesity portends a disadvantage to surgical outcomes at the time of initial surgery affecting survival. METHODS:A retrospective chart review of patient...

journal_title：Gynecologic oncology

authors： Matthews KS,Straughn JM Jr,Kemper MK,Hoskins KE,Wang W,Rocconi RP

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:Lymph node status in endometrial cancer is a major prognostic factor. Sentinel lymph node (SLN) biopsy using radiocolloid and blue dye labeling has emerged as an alternative to systematic lymphadenectomy. This technique requires a preoperative lymphoscintigraphy. The aim of this study was to evaluate the limi...

journal_title：Gynecologic oncology

authors： Ballester M,Rouzier R,Coutant C,Kerrou K,Daraï E

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:To determine if tumor-free distance (TFD) from the uterine serosa predicts surgicopathologic factors and outcome in surgically staged endometrial cancer, and to compare TFD with the traditional estimate of depth of myometrial invasion (DOI). METHODS:Patients who underwent complete surgical staging for primar...

journal_title：Gynecologic oncology

authors： Schwab KV,O'Malley DM,Fowler JM,Copeland LJ,Cohn DE

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:To correlate findings on pathologic examination of loop electroexcisional procedure (LEEP) or cone biopsy specimens with residual disease in radical hysterectomy specimens in patients with stage IA2 cervical cancer to determine whether a subset of such patients may be eligible for conservative, fertility-spar...

journal_title：Gynecologic oncology

authors： Suri A,Frumovitz M,Milam MR,dos Reis R,Ramirez PT

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVES:We aimed to define the site-specific patterns of treatment failure in stage IV ovarian cancer. METHODS:Data from all consecutive Mayo Clinic patients with stage IV epithelial ovarian cancer, from 1994 through 2003, were collected and analyzed. Statistical analyses included the chi(2) test and Kaplan-Meier c...

journal_title：Gynecologic oncology

authors： Aletti GD,Podratz KC,Cliby WA,Gostout BS

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:To determine if extra-peritoneal laparoscopic para-aortic (PA) lymphadenectomy allows a reliable assessment of PA nodes in patients with endometrial cancer (EC). METHODS:In October of 2005, a single surgeon began performing extra-peritoneal laparoscopic PA lymphadenectomy for patients with EC. A prospective ...

journal_title：Gynecologic oncology

authors： Dowdy SC,Aletti G,Cliby WA,Podratz KC,Mariani A

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Bone involvement in endometrial cancer has been described in less than 15% of the patients with metastatic disease. The medical literature reports 29 cases, although none involving the sacrum. CASE:We present a case of a 62-year-old woman who underwent surgery for endometrial adenocarcinoma in December 2002...

journal_title：Gynecologic oncology

authors： Albareda J,Herrera M,Lopez Salva A,Garcia Donas J,Gonzalez R

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVE:To compare surgical morbidity and clinical-pathologic factors for patients with endometrial cancer (EC) undergoing robotic-assisted laparoscopic hysterectomy (RALH) versus total abdominal hysterectomy (TAH) with aortic and/or pelvic lymphadenectomy (LA). METHODS:During the first 14 months of a robotics surgi...

journal_title：Gynecologic oncology

authors： DeNardis SA,Holloway RW,Bigsby GE 4th,Pikaart DP,Ahmad S,Finkler NJ

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVE:To compare the short-term surgical outcome of patients undergoing robotic radical hysterectomy (RRH) versus open radical hysterectomy (ORH) for the treatment of early stage cervical cancer. METHODS:IRB approval was obtained for a retrospective chart review of all radical hysterectomies (RHs) for Stage I and ...

journal_title：Gynecologic oncology

authors： Ko EM,Muto MG,Berkowitz RS,Feltmate CM

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Luteinized thecoma of the ovary associated with sclerosing peritonitis is a rare tumor that has no standard definitive treatment regimen. CASE:A 25 year-old patient diagnosed with luteinized thecoma and sclerosing peritonitis in the omentum. The patient received high dose corticosteroids (IV Hydrocortisone ...

journal_title：Gynecologic oncology

authors： Schonman R,Klein Z,Edelstein E,Czernobilsky B,Fishman A

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Chemotherapy remains an essential part of the treatment of advanced ovarian cancer. Intraperitoneal (IP) administration has been demonstrated to provide a survival advantage over intravenous chemotherapy in three phase 3 studies. However, IP catheter complications have been a significant factor in aborting I...

journal_title：Gynecologic oncology

authors： Bryant CS,Shah JP,Triest JA,Schimp VL,Morris RT

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVES:Chemotherapy is the preferred therapeutic approach for the therapy of advanced ovarian cancer, but a successful long-term treatment is prevented by the development of drug resistance. Recent works have underlined the involvement of non-coding RNAs, microRNAs (miRNAs) in cancer development, with several conje...

journal_title：Gynecologic oncology

authors： Sorrentino A,Liu CG,Addario A,Peschle C,Scambia G,Ferlini C

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVE:To investigate the diagnostic accuracy of the sentinel node procedure in patients with vulvar cancer, a multicenter study was launched in Germany in 2003 involving 7 oncology centers. PATIENTS AND METHODS:Between 2003 and 2006, 127 women with primary T1-T3 vulvar cancer were entered in the study and treated ...

journal_title：Gynecologic oncology

authors： Hampl M,Hantschmann P,Michels W,Hillemanns P,German Multicenter Study Group.

更新日期：2008-11-01 00:00:00

abstract：:Wound healing has evolved from gauze therapy to the use of proteomics, gene therapy, and cellular-based therapies in the short time span of 45 years. Education for health care providers has not kept pace with the logarithmic acceleration in technology development and treatment options. A patient with a non-healing wou...

journal_title：Gynecologic oncology

authors： Ennis WJ,Meneses P,Borhani M

更新日期：2008-11-01 00:00:00

abstract：:As the medical need and expenditure for chronic wound care have increased markedly over the past decade, wound centers have grown exponentially throughout the country. They can be community-based or hospital-based, and in either case, can be run by the facility or by a national chain. The wound center's viability is d...

journal_title：Gynecologic oncology

authors： Attinger CE,Hoang H,Steinberg J,Couch K,Hubley K,Winger L,Kugler M

更新日期：2008-11-01 00:00:00